Δ4-Abiraterone
CHEMICAL COMPOUND
Δ4-abiraterone; CB-7627; CB7627; CB 7627; 17-(3-pyridyl)androsta-4,16-dien-3-one; 17-(3-Pyridyl)androsta-4,16-dien-3-one; D4A; Delta4-Abiraterone; Delta4-abiraterone
Δ4-Abiraterone (D4A; code name CB-7627), also known as 17-(3-pyridyl)androsta-4,16-dien-3-one, is a steroidogenesis inhibitor and active metabolite of abiraterone acetate, a drug which is used in the treatment of prostate cancer and is itself a prodrug of abiraterone (another active metabolite of abiraterone acetate). D4A is formed from abiraterone by 3β-hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD).